The dynamic shifts in submandibular gland stiffness, highlighted by a rise in the second trimester followed by a decrease in the third, most likely signify the hormonal and hemodynamic adaptations that come with pregnancy. These findings underscore the importance of monitoring salivary gland function in pregnant women and pave the way for future investigations into the diagnostic and prognostic implications of these changes. To the best of our knowledge, this represents the inaugural study demonstrating normative stiffness and vascularity parameters of salivary glands across each trimester of pregnancy.
Şara et al. (Sun,) studied this question.