Nanotechnology-Mediated Metabolic Reprogramming for Tumour Ferroptosis: Mechanisms and Therapeutic Prospects

Key Points

• The aim is to explore how nanotechnology can induce ferroptosis in resistant tumor cells through metabolic reprogramming.
• Analyzed mechanisms of ferroptosis triggered by lipid peroxidation
• Investigated the role of nanotechnology in enhancing treatment responses
• Evaluated tumor metabolic pathways affected by treatments
• Nanotechnology significantly increased ferroptosis in resistant tumor types
• Altered metabolic pathways were linked to enhanced treatment efficacy
• Induced lipid peroxidation correlated with reduced tumor viability