Unravelling the Contribution of Matrix Metalloproteinase-3 Genotype-Phenotype to Pterygium Risk

Puntos clave

• The study aims to explore the association between the MMP-3 genotype and the risk of developing pterygium.
• Genetic analysis focusing on MMP-3 rs3025058 variant
• Assessment of its role in susceptibility to pterygium
• Evaluation of extracellular matrix (ECM) regulation.
• Identified MMP-3 rs3025058 as a potential genetic biomarker for pterygium risk
• Found evidence of ECM dysregulation linked to this genotype
• Suggested implications for disease progression and risk assessment.