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Synapse
March 5, 2026American Journal of Veterinary Research0 citationsOpen Access

Histoplasma antigen test results are influenced by the urine collection method in dogs

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KCKatie ComoKAKathleen M. AicherSZSong Zhang

Key Points

  • This research investigates how different urine collection methods affect histoplasma antigen test results in dogs.
  • Comparison of urine collection methods including sterile cystocentesis and others.
  • Assessment of diagnostic accuracy using histoplasma antigen tests.
  • Evaluation of low-level positive test results confirmation.
  • Sterile cystocentesis significantly improves confirmation of low-level positive results.
  • Non-sterile collection methods may lead to false positives or contamination.
  • Higher diagnostic accuracy achieved with sterile collection methods.

Abstract

Clinicians should confirm contam low-level positive results with sterile cysto to improve diagnostic accuracy and clinical decision-making for histoplasmosis in dogs.

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Cite This Study

Como et al. (2026) studied this question.

synapsesocial.com/papers/69a91d21d6127c7a504bfed3https://doi.org/10.2460/ajvr.25.12.0457
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Histoplasma Urinary Antigen for the Diagnosis of Histoplasmosis in Non‐ HIV Individuals2026
  2. 2Lack of Association Between Histoplasma Urine Antigen Values and Clinical Response in Persons without HIV2025 · 1 citations
  3. 3Hematuria Due to Possible Histoplasma-Associated Urinary Bladder Pseudotumor With Negative Serologic and Urine Antigen Testing2024
  4. 4A commercial whole blood polymerase chain reaction assay failed to diagnose histoplasmosis in cats confirmed by cytology or urine antigen detection2024 · 1 citations
  5. 5Histoplasmosis in domestic cats: new minimally invasive diagnostic techniques2024 · 1 citations