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March 5, 2026Communications Medicine0 citationsOpen Access

Efficacy and safety of eribulin plus gemcitabine as second-line treatment for recurrent HER2-negative breast cancer: a phase II, single-arm, open-label trial

XXXiaolu XuJZJincai ZHONGHLHong Lin

Key Points

  • This research aims to evaluate the effectiveness and safety of eribulin combined with gemcitabine for recurrent HER2-negative breast cancer.
  • Phase II, single-arm, open-label trial design
  • Participants received eribulin and gemcitabine as second-line treatment
  • Assessment of treatment efficacy and safety through patient monitoring
  • Eribulin plus gemcitabine demonstrated effectiveness in managing recurrent HER2-negative breast cancer
  • Treatment was well-tolerated with minimal severe side effects
  • Provides a potential second-line treatment option for patients with limited choices

Abstract

Eribulin plus gemcitabine is effective and well-tolerated in patients with HER2-negative metastatic breast cancer needing second-line or later treatment, providing a valuable treatment option.

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Cite This Study

Xu et al. (2026) studied this question.

synapsesocial.com/papers/69a91d55d6127c7a504c006ahttps://doi.org/10.1038/s43856-026-01483-z
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