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Synapse
March 5, 20260 citations

Post-traumatic Hypertrophic Olivary Degeneration with Palatal Myoclonus-A Case Report.

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KBKatherine BaileyJHJacob HansonSKSuad Khalil

Key Points

  • To explore the case of hypertrophic olivary degeneration linked to trauma and the subsequent development of palatal myoclonus.
  • Descriptive case report of a 7-year-old boy post motor vehicle accident
  • Documentation of symptoms including facial twitching and palatal clicking
  • Use of brain MRI and EEG to assess neurological changes
  • Trial of various antiseizure medications, leading to carbamazepine treatment
  • Marked improvement in symptoms with carbamazepine administration
  • MRI findings suggestive of hypertrophic olivary degeneration
  • EEG displayed abnormal facial twitching without electrographic changes
  • Traumatic HOD identified as a rare condition in pediatric patients, with only one prior case reported

Abstract

This is a case report of a 7-year-old boy with a medical history of a motor vehicle accident (MVA) 2 years previously. Two years post-MVA, he developed quivering and twitching of the right side of his lip, palate, and neck. Multiple antiseizure medications were attempted with no effect. However, carbamazepine was started with marked improvement. The most recent brain magnetic resonance imaging showed findings suggestive of hypertrophic olivary degeneration (HOD). Electroencephalography captured the abnormal facial twitching with audible palatal clicking, but was not associated with electrographic changes. This case demonstrates the anatomic importance of the Guillain-Mollaret triangle, as traumatic disruption of this pathway resulted in palatal myoclonus. HOD occurring due to trauma is an incredibly rare etiology, with only 1 other case reported in the literature in a 27-year-old man, with no previous reports of posttraumatic HOD occurring in an individual under 18 discovered during our literature review.

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Cite This Study

Bailey et al. (2026) studied this question.

synapsesocial.com/papers/69a91d6dd6127c7a504c020ehttps://doi.org/10.1177/08830738261417414
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hypertrophic olivary degeneration secondary to a Guillain Mollaret triangle cavernoma: Two case report2024 · 1 citations
  2. 2Hypertrophic olivary degeneration following head injury: a case report2024 · 2 citations
  3. 3Olivary Hypertrophy Induced Palatal Myoclonus in a Treated Case of Medulloblastoma2024
  4. 4Palatal Myoclonus Due to Cortical Cavernous Malformation2024 · 1 citations
  5. 5Another Rare Cause of Hypertrophic Olivary Degeneration Following Cavernous Malformation Hemorrhage: A Case Report2025