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March 5, 2026Insights into Imaging0 citationsOpen Access

The value of gadobenate dimeglumine-enhanced MRI quantification in predicting aggressiveness and prognosis of typical intrahepatic mass-forming cholangiocarcinoma: a multicenter retrospective study

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ZSZhang StBKBing KangCQChenyang Qiu

Key Points

  • The aim is to evaluate MRI's effectiveness in predicting the aggressiveness and prognosis of intrahepatic cholangiocarcinoma.
  • Multicenter retrospective study design
  • Used MRI quantification with gadobenate dimeglumine
  • Analyzed metrics like volume ratio and CA19-9 levels
  • Assessed relationships between imaging findings and survival outcomes
  • Volume ratio and relative intensity ratio are strong predictors of tumor aggressiveness.
  • CA19-9 levels ≥ 34 U/mL associated with poorer survival rates.
  • Tumor boundary features linked to decreased overall survival.
  • Maximum tumor size ≥ 3 cm correlated with shorter disease-free survival.

Abstract

The volume ratio (VR), relative intensity ratio (RIRrim), CA19-9 ≥ 34 U/mL, and necrosis were independent predictors of high aggressiveness. The VR, RIRrim, CA19-9 ≥ 34 U/mL, and tumor boundary were independent predictors of poorer overall survival. The VR, RIRrim, CA19-9 ≥ 34 U/mL, tumor boundary, and tumor maximum size ≥ 3 cm were independent predictors of shorter disease-free survival.

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Cite This Study

St et al. (2026) studied this question.

synapsesocial.com/papers/69a91db5d6127c7a504c0c1dhttps://doi.org/10.1186/s13244-026-02225-4
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