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March 6, 2026Annals of Internal Medicine Clinical Cases0 citationsOpen Access

Fulminant Vibrio vulnificus Infection Following Dog Scratch in a Transplant Recipient Who Is Immunosuppressed: A Case Report

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EKEmily KimACAndrea L. Covington

Key Points

  • To explore a rare case of severe Vibrio vulnificus infection following a dog scratch in an immunosuppressed patient.
  • Patient presented with leg pain after dog scratch
  • Developed necrotizing bullae and septic shock
  • Received surgical intervention and targeted antibiotics
  • De-escalated immunosuppressive therapy
  • Progressed to multiorgan failure and septic shock
  • Recovered fully after 23 days
  • Highlights the need for prompt diagnosis in immunocompromised patients

Abstract

A 58-year-old man who is immunosuppressed presented with severe left leg pain 1 day after sustaining a scratch from his dog, which had been swimming in warm coastal water. He quickly developed necrotizing bullae secondary to Vibrio vulnificus bacteremia, progressing to septic shock and multiorgan failure. Management included prompt surgical intervention, targeted antibiotics, and immunosuppressant de-escalation. Despite his grave prognosis, he recovered after 23 days. This case highlights an unconventional V vulnificus transmission route, underscoring the need for rapid diagnosis and treatment in high-risk patients with compatible symptoms, regardless of direct water exposure.

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Cite This Study

Kim et al. (2026) studied this question.

synapsesocial.com/papers/69aa6f0d531e4c4a9ff5924ahttps://doi.org/10.7326/aimcc.2025.1047
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A50-49 Deadly Waters: Vibrio Vulnificus Sepsis in an Aids Patient2026
  2. 2Vibrio Vulnificus-Induced Septic Shock Complicated by Necrotizing Fasciitis: A Case Report and Review of Clinical Characteristics2026
  3. 3Vibrio vulnificus: A Highly Virulent Bacterium on the Rise.2026
  4. 4Hand salvage using a chimeric alt flap following extensive Vibrio vulnificus necrotizing fasciitis: a case report2026
  5. 5The clinical characteristics and diagnostic and treatment protocol for 14 acute Vibrio vulnificus infections caused by aquatic products2025