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March 6, 2026Lishizhen medicine and materia medica research

inical observation on modified italicZeming Hongshan Decoction/italic （泽明红山方） for metabolic associated fatty liver disease complicated with fatty acid metabolism disorders

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Authors

XGXiaoxuan GENGBLBingjiu LUJZJialian ZHENG

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Overview

Observational analysis shows improved liver function and lipid levels in MAFLD with mixed hyperlipidemia, suggesting potential benefits of herbal treatment.

Key Points

  • The study aims to explore the effects of modified Zeming Hongshan Decoction on metabolic associated fatty liver disease complicated with mixed hyperlipidemia.
  • Patient cases were selected from a liver clinic, adhering to MAFLD and MHLP diagnostic criteria.
  • 62 cases in the control group received silymarin capsules alongside standard treatment; 62 in the herbal group received the decoction.
  • All participants underwent a 12-week treatment period.
  • Biomeasures such as BMI, liver function tests, lipid levels, and fibrosis indexes were compared pre- and post-treatment.
  • Both groups experienced significant reductions in BMI, with the herbal group showing better outcomes (P<0.05).
  • Improvements in liver function, lipid profiles, and fibrosis indicators were noted in both groups.
  • The herbal group exhibited higher efficacy in clinical symptoms and imaging results.
  • No adverse effects were recorded, indicating good safety of the treatment.

Cite This Study

GENG et al. (2026) studied this question.

synapsesocial.com/papers/69aa7037531e4c4a9ff59c1bhttps://doi.org/10.70976/j.1008-0805.szgygy-2026-0117
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