This research aims to develop a new fluorescent probe to specifically image lipid droplets in both live and fixed cells.
Developed a novel fluorescent probe, TPE-Q, for targeting lipid droplets.
Tested the probe’s effectiveness in live and fixed cell environments.
Assessed interactivity of the probe with lipid droplets under various conditions.
The new probe showed strong fluorescence specific to lipid droplets.
Demonstrated successful imaging in both living and fixed cell systems.
Enabled clearer observation of lipid droplets compared to existing methods.
Abstract
Lipid droplets(LDs) play an vital role in energy homeostasis and cellular signaling. Therefore, the visualization of LDs is very important. To this end, a new LD-specific fluorescent probe, TPE-Q, was...