The presented work comprehensively evaluates the influence of various parameters on the comparison of upright and supine therapy of thoracic patients. A solid understanding of these parameters is paramount to reduce bias in future larger patient cohort studies on the viability of upright positioning. The final dosimetric comparison between postures highly depends on patient characteristic and the investigated parameter. More data are needed to provide a resilient comparison between postures.
Martire et al. (Sun,) studied this question.