Nearly one-third of patients with preexisting vasculitis experienced a disease flare during ICI therapy, with one fatal case. For most, outcomes were favorable with effective flare management. Preexisting vasculitis should not be considered an absolute contraindication for cancer immunotherapy with ICI.
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Juan Sevillano
Amin H. Nassar
Yixuan Zhou
The University of Texas MD Anderson Cancer Center
Cleveland Clinic
The University of Texas Health Science Center at Houston
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Sevillano et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69ada962bc08abd80d5bcadc — DOI: https://doi.org/10.1002/acr2.90003