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March 10, 2026Cancer0 citations

Two new options for NPM1 ‐mutated relapsed, refractory acute myeloid leukemia

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LLLeah Lawrence

Key Points

  • The aim is to inform about new FDA approvals for treating specific leukemia mutations.
  • Reviewed FDA announcements regarding new treatments
  • Highlighted specific approvals for relapsed or refractory acute myeloid leukemia
  • Mentioned treatments for other related conditions
  • Revumenib and ziftomenib approved for NPM1-mutated acute myeloid leukemia
  • Daratumumab with hyaluronidase-fihj approved for high-risk smoldering multiple myeloma
  • Oral TKI sevabertinib approved for advanced HER2-mutant NSCLC

Abstract

This news section offers Cancer readers timely information on events, public policy analysis, and topical issues. In this issue, the FDA recently approved two menin inhibitors for the treatment of relapsed or refractory acute myeloid leukemia with NPM1 mutations: revumenib and ziftomenib. In addition, the FDA also approved the subcutaneous injection of anti‐CD38 monoclonal antibody daratumumab and hyaluronidase‐fihj for patients with high‐risk smoldering multiple myeloma, and oral TKI sevabertinib is approved for advanced HER2 ‐mutant NSCLC.

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Cite This Study

Leah Lawrence (2026) studied this question.

synapsesocial.com/papers/69af944f70916d39fea4b537https://doi.org/10.1002/cncr.70275
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