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March 10, 2026Medicina Clínica0 citationsOpen Access

Effect of walking exercise on liver enzymes in children with phenylketonuria and non-alcoholic fatty liver disease: A randomized controlled trial

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AIAli Mohamed Ali IsmailMGMahmoud M. GoharySBShaimaa Mohamed Mabrouk Bondok

Key Points

  • This research aims to assess the impact of walking exercise on liver enzymes in children with phenylketonuria and non-alcoholic fatty liver disease.
  • Conducted an 8-week free walking exercise program
  • Involved children with PKU and NAFLD
  • Measured changes in BMI and liver enzyme levels
  • Significant improvement in BMI
  • Reduction in liver enzymes: AST, ALP, ALT, GGT, and TG

Abstract

Participation in an 8-week free walking program significantly improves BMI, AST, ALP, ALT, GGT, and TG in children with NAFLD and PKU.

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Cite This Study

Ismail et al. (2026) studied this question.

synapsesocial.com/papers/69af94c970916d39fea4bae4https://doi.org/10.1016/j.medcli.2026.107395
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Growth assessment in children with phenylketonuria.2025
  2. 2Cognition after a 4-week high phenylalanine intake in adults with phenylketonuria – a randomized controlled trial2024 · 13 citations
  3. 3Carnitine, Amino Acids, Vitamins, and Hematological Status in Children with Classical Phenylketonuria: A Case–Control Study2026
  4. 4Evaluation of Body Composition and Biochemical Parameters in Adult Phenylketonuria2024
  5. 5Neurodevelopmental Outcome of Children with Phenylketonuria after Early Neonatal Screening2024