What question did this study set out to answer?

The aim is to establish a sustainable protocol for C3-alkylation of quinoxaline-2-ones using g-C3N4 as a photocatalyst.

March 10, 2026Advanced Synthesis & Catalysis0 citations

Metal‐Free Decarboxylative Alkylation of Quinoxaline‐2(1 H )‐ones Enabled by Heterogeneous g‐C 3 N 4 Photoredox Catalysis

Puntos clave

The aim is to establish a sustainable protocol for C3-alkylation of quinoxaline-2-ones using g-C3N4 as a photocatalyst.
Utilized graphitic carbon nitride as a heterogeneous photocatalyst for alkylation.
Conducted reaction under mild conditions with O2 as the oxidant.
Assessed the method's tolerance to diverse functional groups.
Evaluated catalyst recycling over five cycles.
Achieved alkylation yields ranging from 65% to 92%.
The g-C3N4 catalyst showed maintained activity over multiple cycles.
Demonstrated cost and environmental benefits compared to traditional methods.

Resumen

A sustainable protocol for the direct C3‐alkylation of quinoxalin‐2‐ones using graphitic carbon nitride (g‐C 3 N 4 ) as a heterogeneous photocatalyst is reported. This article is the first to use g‐C 3 N 4 to enable N‐heterocyclic alkylation via direct decarboxylation, thereby overcoming the limitations of homogeneous Ir/Ru systems. The reaction proceeds under mild conditions with O 2 as the oxidant, tolerating diverse functional groups and affording products in 65%–92% yields. The g‐C 3 N 4 catalyst, prepared from earth‐abundant precursors, is readily recycled by centrifugation and maintains its activity over five cycles. This method offers advantages in cost, environmental impact, and scalability, making it a green and promising candidate for industrial applications.

Preguntar a la IA

Me gusta

Guardar

Ver artículo completo