March 10, 2026Asian Pacific Journal of Cancer Prevention0 citationsOpen Access
Salivary Malondialdehyde as a Marker of Oxidative Stress in Tobacco Chewers, with and without Oral Submucous Fibrosis: A Comparative, Cross-Sectional Biochemical Study
The study aims to evaluate salivary malondialdehyde (MDA) levels as an indicator of oxidative stress in tobacco chewers, specifically comparing those with and without oral submucous fibrosis.
Cross-sectional design involving tobacco chewers
Measurement of salivary malondialdehyde (MDA) levels
Comparative analysis between groups with and without oral submucous fibrosis
Elevated levels of salivary MDA found in patients with oral submucous fibrosis compared to those without
Correlation established between higher MDA levels and increased disease severity
Findings suggest a significant role of oxidative stress in the pathology of oral submucous fibrosis
Abstract
Elevated salivary MDA levels in oral submucous fibrosis patients reflect increased oxidative stress and its correlation with disease severity.