ABSTRACT Giant frontal sinus mucoceles, caused by ostial obstruction, can lead to severe complications such as headaches, vision impairment, and brain compression. Early diagnosis through imaging and prompt surgical intervention, such as craniotomy, is critical to remove mucopurulent debris and necrotic bone, preventing vision loss and intracranial complications. For giant frontal sinus mucoceles with extensive bony necrosis and intracranial extension, open craniotomy for complete debridement of mucopurulent debris and necrotic bone may be necessary over endoscopic marsupialization to prevent recurrence and intracranial complications, despite the trend toward minimally invasive surgery.
Ghimire et al. (2026) studied this question.