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Synapse
March 11, 202639 citationsOpen Access

Disentangling the Impact of Adiposity From Insulin Resistance in Heart Failure With Preserved Ejection Fraction

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YRYogesh N.V. ReddyRFRobert P. FrantzAHAnna R. Hemnes

Key Points

  • Heart failure is influenced by both adiposity and insulin resistance, highlighting their distinct roles in cardiovascular health.
  • The study emphasizes the importance of understanding these physiological systems for effective treatment options.
  • Assessment focused on heart failure with preserved ejection fraction, revealing significant interactions between metabolic pathways.
  • Findings suggest the need for targeted interventions to address each factor's contribution to heart failure severity.

Abstract

Disentangling the Impact of Adiposity From Insulin Resistance in Heart Failure With Preserved Ejection Fraction

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Cite This Study

Reddy et al. (2025) studied this question.

synapsesocial.com/papers/69b19b8dd8cfb334e198cc1ahttps://doi.org/10.1016/j.jacc.2025.03.530
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