Precision Nutrition in Meat Matrices: The Delicate Nutrient Delivery Model (DNDM) for Lifecycle-Specific Health

• Meat provides vital macronutrients and micronutrients, crucial for diverse population groups' health. • The DNDM enhances nutrient bioavailability in meat using meat processing technology and nutrition fortification technology. • The DNDM facilitates the development of personalized meat products, addressing specific nutritional needs and preventing deficiencies. Meat matrices serve as pivotal reservoirs of high-quality proteins and bioavailable micronutrients essential for human health. However, the "one-size-fits-all" approach to meat consumption fails to address the profound heterogeneity in nutritional requirements across the lifespan, ranging from rapid neurodevelopment in infants to anabolic resistance in the elderly. This review systematically explores the Delicate Nutrient Delivery Model (DNDM) as a transformative framework for precision nutrition. We first analyze the distinct nutritional profiles of meat, including proteins, bioactive peptides, and micronutrients, and align them with the specific physiological barriers and metabolic demands of diverse demographic groups. Subsequently, we critically evaluate the engineering strategies underpinning DNDM, including non-thermal processing, lipid-based nanocarriers (liposomes, solid lipid nanoparticles), Pickering emulsions, and 3D printing, which are designed to protect labile nutrients and optimize their release kinetics. The implementation of DNDM is then assessed across populations, highlighting its role in correcting metabolic deviations in adolescents, enhancing recovery in athletes, and preventing sarcopenia in geriatric groups. Ultimately, this work highlights the potential of DNDM to bridge the gap between advanced food processing and personalized health needs. By shifting the focus from "what we eat" to "how nutrients are delivered," this review provides a roadmap for unlocking the full functional potential of meat matrices for public health.