What does this research mean for the field?

Desulfonylcyanamidation of α,β-unsaturated sulfones with N-tosyl N-aryl cyanamides provides a novel method for accessing N-cyanoenaminones. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to explore a new reaction method for synthesizing N-cyanoenaminones from α,β-unsaturated sulfones.

March 12, 2026

Desulfonylcyanamidation of α,β-Unsaturated Sulfones with N-tosyl N-Aryl Cyanamides (NCTS): Access to N-Cyanoenaminones

Key Points

The aim is to explore a new reaction method for synthesizing N-cyanoenaminones from α,β-unsaturated sulfones.
Desulfonylcyanamidation reaction
Used N-tosyl N-aryl cyanamides
Investigated reaction conditions and outcomes
Successfully synthesized N-cyanoenaminones
Demonstrated versatility in building block applications
Potential implications for pharmaceutical synthesis

Abstract

Enaminones are versatile building blocks with widespread applications in the synthesis of biologically active molecules, natural products, and synthetic pharmaceutical agents. Herein, we describe a desulfonylcyanamidation between α,β-unsaturated sulfones and...

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Discussion

Authors

Chengxian Guo

Qiaoyan Xing

Hongding Xie

Journals

Chemical Communications

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Desulfonylcyanamidation of α,β-Unsaturated Sulfones with N-tosyl N-Aryl Cyanamides (NCTS): Access to N-Cyanoenaminones

Key Points

Abstract

Citation Network

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Discussion

Authors

Journals

Actions

References and Citations

Citation Network

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Discussion

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