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March 12, 2026Cell Reports Medicine0 citationsOpen Access

LIFUS-driven engineered bacteria reprogram immunosuppressive niches via mechano-NOTCH signaling

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LLLizhou LinXLXiao LiWGWenyun Guo

Key Points

  • The aim is to explore how engineered bacteria can alter immunosuppressive niches using mechano-NOTCH signaling.
  • Development of LIFUS-driven engineered bacteria
  • Assessment of immunosuppressive niche reprogramming
  • Analysis of mechano-NOTCH signaling pathways
  • Engineered bacteria effectively reprograms immunosuppressive environments.
  • Mechano-NOTCH signaling pathways are significantly activated.
  • Potential therapeutic implications for enhancing immune responses observed.

Abstract

Publisher of over 50 scientific journals across the life, physical, earth, and health sciences, both independently and in partnership with scientific societies including Cell, Neuron, Immunity, Current Biology, AJHG, and the Trends Journals.

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Cite This Study

Lin et al. (2026) studied this question.

synapsesocial.com/papers/69b2580996eeacc4fcec7457https://doi.org/10.1016/j.xcrm.2026.102658
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