Clinical Value of HbA1c/updatedGMI Ratio in Identifying Early Retinopathy Risk in Type 1 Diabetes.

Key Points

• Investigate the association between the HbA1c/updated GMI ratio and the risk of developing diabetic retinopathy (DR) in type 1 diabetes (T1D).
• Analyzed the HbA1c/updated GMI ratio in individuals with T1D.
• Evaluated correlations with non-HDL-C and RBC indices as markers of glycation.
• Determined the threshold for HbA1c/updated GMI ratio linked to diabetic retinopathy risk.
• An HbA1c/updated GMI ratio ≥1.05 is associated with increased odds of retinopathy.
• High non-HDL-C levels and RBC indices correlate with elevated glycation.
• Further studies are needed to establish definitive cutoff values for risk assessment.

Abstract