Analysis reveals that female patients have better long-term survival rates than male patients, suggesting possible gender-related differences in tumor characteristics.
Key Points
This research aims to identify factors that influence long-term survival in patients with advanced leiomyosarcoma (LMS).
Analyzed data from 402 patients with advanced LMS.
Compared baseline characteristics, tumor location, and histologic subtype distributions by sex.
Evaluated overall survival (OS) and disease-free survival (DFS) rates between male and female patients.
Female patients exhibited significantly higher 5-year OS (81% vs. 66%) and DFS (72% vs. 59%) compared to males.
Differences in tumor subtype distributions were noted, with more LMS in females (22% vs. 9.4%).
Postoperative radiotherapy was administered more frequently in females (18% vs. 11%).