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March 12, 2026Frontiers in Genetics0 citationsOpen Access

Navigating tensions between scientific advancement and ethical practice in biobanking: a qualitative study in Japan

MOMasanori OikawaYTYoshiyuki Takimoto

Key Points

  • The study investigates the governance systems in Japanese biobanks and the challenges faced in implementation.
  • Conducted semi-structured interviews with biobank professionals in Japan
  • Analyzed governance policies and their practical challenges
  • Identified themes related to management and ethical considerations
  • Highlighted three main themes: organizational governance, utilization rates, and stakeholder management
  • Revealed tensions between scientific advancement and ethics in biobank operations
  • Identified a lack of systematic research on governance policies in Japan

Abstract

The long-term sustainability of biobanking depends on governance systems that are both ethically robust and operationally reliable. Despite this importance, only a limited number of empirical studies have examined which governance policies are actually implemented in biobank operations and what challenges arise in practice. This lack of systematic research is particularly evident in Japan. To address this gap, we conducted semi-structured interviews with professionals involved in the operation and management of four Japanese biobanks. The study aimed to elucidate the underlying concepts and policies of organizational governance, as well as the challenges encountered in their implementation. The analysis generated three main themes: (a) organizational management and governance; (b) expansion of the scope of utilization and improvement of utilization rates and efficiency; and (c) stakeholders and research governance. These themes reflect the tension inherent in biobanks as medical research infrastructure between scientific advancement and ethical practice. It was within this tension that governance was conceived and enacted in everyday practice.

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Cite This Study

Oikawa et al. (2026) studied this question.

synapsesocial.com/papers/69b25abe96eeacc4fcec8b44https://doi.org/10.3389/fgene.2026.1778587
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