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March 12, 2026Journal of Comparative Effectiveness Research0 citationsOpen Access

Performance of stenting in femoropopliteal disease: a systematic literature review and meta-analysis of proportions

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YGY. GouefficASAntonia Bosworth SmithFDFabian Distler

Key Points

  • The study aims to assess the effectiveness of various stent types in femoropopliteal lesions over different time points.
  • Conducted a systematic review to identify studies with at least 50 patients published from 2009 to 2024.
  • Extracted data on patient and lesion characteristics and outcomes from selected studies.
  • Performed subgroup analyses based on lesion length and study quality.
  • Applied random-intercept logistic regression to pool the data.
  • Analyzed data from 141 out of 870 studies, involving 35,897 patients.
  • Eluvia stents showed the highest primary patency and low revascularization rates at 12 and 24 months.
  • Mortality rates remained stable for short lesions but were more variable for longer lesions.

Abstract

Aim: To evaluate the performance of four stent types (BMS, bare metal stents; Eluvia, a polymer-based paclitaxel-eluting stent; Viabahn, a covered stent; and Zilver PTX, a polymer-free paclitaxel-coated stent) in femoropopliteal lesions at 12 and 24 months using a meta-analysis of proportions. Materials 69.6% were male. The overall mean lesion length was 153.1 (range: 37-330) mm. Although all stent types performed well in the main analysis, Eluvia exhibited consistently high primary patency and low target lesion revascularization rates at both timepoints and across lesion lengths. Mortality rates for all stent types were stable for short lesions but more variable for long lesions. Conclusion: All stents used in short lesions performed well; however, Eluvia also demonstrated reliable performance in long lesions.

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Cite This Study

Goueffic et al. (2026) studied this question.

synapsesocial.com/papers/69b25b4996eeacc4fcec9c9dhttps://doi.org/10.57264/cer-2025-0152
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