Effects of highly leukotoxic Aggregatibacter actinomycetemcomitans associated with ligature-induced periodontitis on oral and gut tissues in male rats

Key Points

• This research investigates how Aggregatibacter actinomycetemcomitans affects periodontitis and gut health.
• Gastric inoculation of male rats with Aggregatibacter actinomycetemcomitans JP2 strain
• Induction of ligature-induced periodontitis
• Assessment of oral and gut tissue changes
• Gastric inoculation worsened ligature-induced periodontitis symptoms
• Observed significant intestinal morphological changes independent of periodontitis

Abstract