Parkinson's Disease increased the risk of cardiovascular-related deaths by 82% compared to those without Parkinson's Disease, with an HR of 1.82 (95% CI 1.24-2.69; p=0.002).
Patients with Parkinson's disease and cardiovascular disease
Incidence, severity, and mortality of Parkinson's disease in relation to cardiovascular health
This review highlights a significant but complex interplay between cardiovascular disease and Parkinson's disease, suggesting that cardiovascular comorbidities worsen PD prognosis and mortality.
Parkinson's disease (PD) is a common neurodegenerative disorder that is becoming increasingly prevalent in the United States.Current research suggests a possible bidirectional relationship between cardiovascular disease (CVD) and PD.This review aims to synthesize relevant evidence to analyze the interplay between CVD and PD.Researchers utilized academic databases to find current and relevant studies that met the defined inclusion and exclusion criteria.After reviewing various articles, a majority of evidence suggests a correlation between CVD and worsening prognosis for PD patients regarding mortality, cardiac dysfunction, and blood pressure.Conflicting and inconclusive studies are acknowledged within this
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Christopher George
Gurneer Sidhu
Hridini Dave
SHILAP Revista de lepidopterología
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George et al. (Mon,) conducted a review in Parkinson's Disease (n=28,242). Parkinson's Disease increased the risk of cardiovascular-related deaths by 82% compared to those without Parkinson's Disease, with an HR of 1.82 (95% CI 1.24-2.69; p=0.002).
www.synapsesocial.com/papers/69b3aaa802a1e69014ccb718 — DOI: https://doi.org/10.32596/jucvm.galenos.2026.2025-12-147