The SYN-OCT dataset contains a total of 200,000 synthetic cross-sectional circumpapillary optical coherence tomography (OCT) images, comprising of 100,000 images from a generative image model for glaucoma eyes and 100,000 from a generative image model for healthy normal eyes. The generative image models were developed using real OCT imaging data acquired from study participants at the Singapore Eye Research Institute, and were trained with the respective real images from glaucoma or healthy eyes. Structural characteristics of the synthetic data were validated and found to be comparable with the real data using an automated segmentation approach. These measurements are provided together with the synthetic images. We envision this dataset to be useful for the development or validation of deep learning applications for glaucoma analysis and detection, and as a dataset to study the synthetic generation of medical images and their usability. This dataset is publicly available.
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Damon Wong
Ashish Jith Sreejith Kumar
Rachel S. Chong
Scientific Data
National University of Singapore
Nanyang Technological University
Medical University of Vienna
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Wong et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69b3aaa802a1e69014ccb78a — DOI: https://doi.org/10.1038/s41597-026-06946-5