The Relationship Between Blood Groups and Hidradenitis Suppurativa: A Retrospective Evaluation

Aims: This study aims to investigate the potential relationship between ABO blood groups and the incidence of hidradenitis suppurativa.Methods: This retrospective study included adult patients with clinically diagnosed hidradenitis suppurativa followed at a tertiary dermatology clinic (2019–2023) and healthy controls. ABO and Rh blood groups were determined using standard agglutination methods. Statistical analyses were performed using chi-square and t-testsResults: A total of 100 patients with hidradenitis suppurativa and 365 healthy controls were included in the analysis. The distribution of ABO blood groups was comparable between the two groups (p=0.650). Blood group A Rh (+) was the most common in both patients (40%) and controls (39.2%), followed by O Rh(+) (30% vs. 27. 1%). Similarly, the Rh factor distribution showed no significant difference, with 89% of patients and 89.6% of controls being Rh positive (p=1.000). When ABO and Rh blood groups were evaluated together, the overall distribution remained statistically similar across groups (p=0.958).Conclusions: This study found no significant association between ABO or Rh blood groups and the occurrence of hidradenitis suppurativa. Further studies with larger and more diverse populations are needed to confirm these findings and investigate potential underlying mechanisms.