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Synapse
March 13, 20260 citations

Bridging genomics and pharmacoepidemiology to expand treatment options for alcohol use disorder.

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CRChristopher T RentschSMSamantha G MaloneMSMingjian Shi

Key Points

  • To align genomic findings with clinical data for enhancing treatment options for alcohol use disorder (AUD).
  • Integrated genomic findings with real-world clinical data.
  • Identified and prioritized drug repurposing candidates.
  • Focused on candidates suited for randomized trials.
  • Provided an efficient method for identifying candidates.
  • Highlight potential pharmacotherapies for AUD.

Abstract

This approach, which aligns genomic findings with real-world clinical data, provides an efficient method for identifying promising drug repurposing candidates and prioritizing those that merit evaluation in randomized trials to ultimately advance pharmacotherapies for AUD.

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Cite This Study

Rentsch et al. (2026) studied this question.

synapsesocial.com/papers/69b3ac7002a1e69014cce1c0https://doi.org/10.1111/acer.70247
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