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March 13, 2026Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine0 citationsOpen Access

Replacement of the intracytoplasmic sperm injection (ICSI) holding pipette with a microfabricated device (microICSI) reduces changes to oocyte shape during sham injection of human oocytes

RKRebecca L. KelleyCTCody ThomasDGDavid K. Gardner

Key Points

  • The aim is to evaluate the effectiveness of a microfabricated device in minimizing oocyte distortion during sperm injection.
  • Comparison of microICSI device against traditional ICSI holding pipette
  • Assessment of oocyte shape before and during injection
  • Evaluation of overall procedure time
  • MicroICSI device significantly reduces oocyte shape distortion
  • No reduction in injection funnel size was observed
  • Procedure time remains unchanged

Abstract

The microICSI device reduced distortion in oocyte shape caused by the holding pipette before and during injection, although it did not reduce injection funnel size or overall procedure time.

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Cite This Study

Kelley et al. (2026) studied this question.

synapsesocial.com/papers/69b3acb202a1e69014cce944https://doi.org/10.5653/cerm.2025.08144
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Microfluidic Intracytoplasmic Sperm Injection (MICSI): A Novel Platform for Sperm Isolation, Selection, and Injection Into Oocytes2026 · 3 citations
  2. 2P-103 Sperm selection for ICSI by rheotaxis and thermotaxis in In-Situ handmade microfluidics of fluidic walls: preliminary results of a Randomized Controlled Trial2024 · 1 citations
  3. 3Indications for Micro‐Injection of Sperm in Assisted Reproduction: A Consensus Statement2026
  4. 4O-184 Piezo-ICSI reduces oocyte degeneration, improves ICSI success rates and has shown less dependence on the experience level of embryologists: cumulative data with 65,033 MII oocytes2024 · 1 citations
  5. 5Eye tracking reveals expert gaze patterns during intracytoplasmic sperm injection2026