Combined pharmacological and non-pharmacological interventions effectively reduce depression severity in recent stroke patients, but long-term efficacy in recent MI is unproven.
Does a holistic, multidisciplinary approach encompassing pharmacological and non-pharmacological interventions reduce depression severity or risk in patients with recent stroke or myocardial infarction?
Multidisciplinary interventions reduce depression after stroke, but evidence for long-term efficacy after myocardial infarction remains lacking.
A holistic, multidisciplinary, and tailored approach encompassing pharmacological treatments together with non-pharmacological interventions (psychological therapy, device-based stimulation, and physical activity/exercise) is beneficial in reducing depression severity or risk amongst those with recent stroke, but there is a lack evidence for the long-term efficacy amongst those with recent MI.
Poostchi et al. (2026) studied this question. Combined pharmacological and non-pharmacological interventions effectively reduce depression severity in recent stroke patients, but long-term efficacy in recent MI is unproven.