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March 14, 2026Veterinary Surgery0 citationsOpen Access

Delivery of AgNP led to more pronounced local retention in the subcutaneous versus intraperitoneal location with limited uptake and toxic effects in rats

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MRMarije RisseladaMAMakensie L. AndersonMBMiriam Bates

Key Points

  • The aim is to evaluate the retention and systemic effects of AgNP delivered in different locations in rats.
  • Evaluated AgNP delivery in subcutaneous and intraperitoneal locations in rats.
  • Assessed local retention and uptake as well as toxic effects after delivery.
  • AgNP showed more local retention in the subcutaneous location compared to intraperitoneal.
  • Limited uptake and toxic effects were observed with AgNP delivery.

Abstract

Use of AgNP-P407 may be possible without systemic effects and prolonged local presence, but further testing is needed.

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Cite This Study

Risselada et al. (2026) studied this question.

synapsesocial.com/papers/69b4ad7918185d8a39800d38https://doi.org/10.1111/vsu.70087
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