Oral adjuvants supplemented to phototherapy as a therapeutic strategy for neonatal hyperbilirubinemia: a systematic review

Puntos clave

• To evaluate the effectiveness of oral adjuvants in conjunction with phototherapy for neonatal hyperbilirubinemia.
• Systematic review of existing studies on oral adjuvants and phototherapy.
• Assessment of efficacy and safety data from various trials.
• Evaluation of heterogeneity and bias in the included studies.
• Highlighted variability in outcomes due to study differences.
• Identified potential biases that limit conclusive results.
• Recommended the need for large, multicenter randomized trials to solidify findings.