Immunological Strategies Against Antimicrobial Resistance: Emerging Solutions in Veterinary and One Health Frameworks

The ever-increasing risk of antimicrobial resistance (AMR) is a major concern to worldwide health and veterinary medicine is a key factor in its growth and its solution. This chapter dwells on the cutting-edge immunological measures designed and implemented in the fight against AMR in animal wellbeing. It highlights the integrative measures of using the traditional veterinary-based practices, alongside novelty Immunotherapeutics such as vaccines, monoclonal antibodies, immunomodulators, and host-directed structures. The chapter explains the ways that can be used to minimize antibiotic dependency by taking advantage of the developments in the field of immunology, including the knowledge of the innate and adaptive immunities as well as microbiome-immune environment communication and pathogen- specific tactics of immunoreaction. Further, it emphasizes the relevance of One Health approach in planning sustainable and effective immunological interventions considering the health of animals, people, and the environment. Seeking to offer in-depth review of the ongoing struggle against AMR to achieve animal welfare and human health using immunological tools, this chapter can be thought of as a compilation of case studies and the latest research describing the movement towards the evolution of combating AMR in veterinary practice.