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March 14, 2026Open MedicineOpen Access

Therapeutic potential of vitamin D in improving antioxidant defense and blood rheology in a rat model of experimental diabetes mellitus

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Authors

NSN. SakhanberidzeMNM NamoradzeNCNino Charkviani

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Overview

Preventive vitamin D improves oxidative stress and blood rheology in rats with diabetes, highlighting its therapeutic potential.

Key Points

  • To evaluate the effects of vitamin D on antioxidant defense and blood rheology in diabetic rats.
  • Used forty male rats, randomly assigned to four groups including diabetic and vitamin D-supplemented groups.
  • Induced diabetes with streptozotocin and administered vitamin D orally at 300 IU/day.
  • Evaluated blood samples for antioxidant parameters and blood rheology on the 21st day.
  • Vitamin D improved antioxidant-related parameters in diabetic rats.
  • Supplementation enhanced blood rheological indices, especially with therapeutic administration.

Cite This Study

Sakhanberidze et al. (2026) studied this question.

synapsesocial.com/papers/69b4ba3618185d8a39803028https://doi.org/10.1515/med-2026-1403
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