Acute and Chronic Changes in Irisin, Myonectin, Myostatin, and Asprosin According to Sex and Aerobic Exercise Intensity in Adults with Obesity

Key Points

• The study aims to analyze acute and chronic hormonal changes in response to exercise intensity and sex in obese adults.
• Randomly assigned 40 obese adults, 20 men and 20 women, to moderate and high-intensity aerobic exercise groups.
• Measured blood levels and body composition pre- and post-exercise sessions and after 8 weeks of aerobic training.
• Evaluated the effects of exercise intensity on irisin, myonectin, myostatin, and asprosin.
• High-intensity aerobic exercise significantly reduced asprosin in both sexes.
• Irisin increased significantly only in the male high-intensity group.
• After 8 weeks, high-intensity exercise improved body composition and increased irisin and myonectin while decreasing myostatin and asprosin in both sexes.
• Moderate exercise showed limited changes, especially in women where myonectin only increased in the high-intensity group.