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March 14, 2026Environmental Science Processes & Impacts0 citationsOpen Access

Caenorhabditis elegans fed native gut microbiota have altered bioenergetic pathway utilization impacting mitochondrial function and susceptibility to pollutants

CBChristina M. BergemannLJLaura E. JamesonIKIsabel W. Kenny-Ganzert

Key Points

  • This research aims to examine how the gut microbiome affects bioenergetic pathway utilization and mitochondrial function in Caenorhabditis elegans.
  • Feeding Caenorhabditis elegans with native gut microbiota
  • Assessing shifts in bioenergetic pathways
  • Evaluating mitochondrial function
  • Analyzing susceptibility to pollutants
  • Altered utilization of bioenergetic pathways observed in the worms
  • Impact on mitochondrial function reported
  • Increased susceptibility to environmental pollutants noted

Abstract

The gut microbiome can influence host health by facilitating digestion, immune function, and xenobiotic metabolism. Microbial metabolites can influence mitochondrial function by shifting bioenergetic pathways, potentially altering sensitivity to mitochondrial...

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Cite This Study

Bergemann et al. (2026) studied this question.

synapsesocial.com/papers/69b4fc1fb39f7826a300ccd6https://doi.org/10.1039/d5em00624d
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