To explore inflammatory heterogeneity in Alzheimer's disease and identify potential biomarkers for diagnosis and treatment.
Analyzed plasma samples from the Bio-Hermes cohort
Assessed cytokine levels using appropriate assays
Performed comparative analysis across Alzheimer's disease spectrum
Identified diverse plasma cytokine profiles in Alzheimer's disease patients
Highlighted specific inflammatory biomarkers as potential therapeutic targets
Demonstrated variations in inflammatory responses across the disease spectrum
Abstract
This exploratory study reveals biologically plausible, inflammatory heterogeneity in AD and highlights plasma cytokine profiles as candidate biomarkers and therapeutic targets, warranting investigation.