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March 14, 2026Chinese Medical JournalOpen Access

Global burden of ischemic heart disease from 1990 to 2021: Findings from the Global Burden of Disease Study 2021 and predictions to 2030

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Population

Global population across all age groups and genders

Design

Global Burden of Disease Study 2021 analysis and prediction model to 2030

Key result

From 1990 to 2021, the age-standardized rates for ischemic heart disease prevalence, incidence, and mortality declined across all age groups globally.

Authors

SJShengyu JingACAo ChenYXYan Xia

Discussion

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Overview

Current IHD prevention remains effective; confirms global progress while extending need for region-specific strategies.

Key Points

  • This research aims to assess the global burden of ischemic heart disease (IHD) from 1990 to 2021 and predict trends up to 2030.
  • Analysis of IHD cases from 1990 to 2021 using Global Burden of Disease Study data.
  • Calculation of age-standardized rates (ASRs) for prevalence, incidence, disability-adjusted life years (DALYs), and mortality.
  • Trend projections for 2030 focusing on different socio-demographic index (SDI) regions.
  • The absolute number of IHD cases increased globally from 1990 to 2021.
  • Age-standardized rates declined in prevalence, incidence, and mortality across all demographics.
  • Significant reductions in incidence rates projected for individuals aged 70 and above by 2030.

Structured PICO

P
Population
Global population assessed for ischemic heart disease burden from 1990 to 2021
O
Outcome
Age-standardized rates (ASRs) for prevalence, incidence, DALYs, and mortality of ischemic heart disease

While the absolute number of global IHD cases has increased from 1990 to 2021, age-standardized rates of incidence and mortality have declined, highlighting the need for region-specific prevention strategies.

Cite This Study

Jing et al. (2026) studied this question. From 1990 to 2021, the age-standardized rates for ischemic heart disease prevalence, incidence, and mortality declined across all age groups globally.

synapsesocial.com/papers/69b4fc7fb39f7826a300d6f4https://doi.org/10.1097/cm9.0000000000004006
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