Nodular pulmonary amyloidosis is a rare entity characterized by extracellular deposits of amyloid protein in the pulmonary parenchyma, usually with a benign prognosis and often asymptomatic. We report a case of a 61-year-old man with a prior diagnosis of Sjögren’s syndrome who, during routine follow-up, was found to have multiple asymptomatic pulmonary nodules in the right lung, with uptake on positron emission tomography-computed tomography (PET CT) (SUVmax 2.11). Surgical resection was performed, and histological analysis revealed nodular deposits of amyloid protein with kappa light chain predominance, without evidence of systemic involvement. This case highlights the importance of considering nodular pulmonary amyloidosis in the differential diagnosis of pulmonary nodules in patients with Sjögren’s syndrome, emphasizing the need for histological evaluation to avoid misdiagnosis and inappropriate treatment.
Building similarity graph...
Analyzing shared references across papers
Loading...
Raquel Borrego
André Soveral
Sandra André
Cureus
Building similarity graph...
Analyzing shared references across papers
Loading...
Borrego et al. (Fri,) studied this question.
www.synapsesocial.com/papers/69b6068883145bc643d1c818 — DOI: https://doi.org/10.7759/cureus.105145