Implications of Acetylator Status and Therapeutic Drug Monitoring of Plasma Rifampicin and Isoniazid Concentrations among Indians

Key Points

• This research aims to explore the relationship between acetylator status and the plasma concentrations of rifampicin and isoniazid in tuberculosis treatment.
• Assessment of acetylator status among patients
• Measurement of plasma concentrations of rifampicin and isoniazid
• Implementation of Therapeutic Drug Monitoring strategies
• Identified abnormal plasma concentrations of rifampicin and isoniazid
• Demonstrated acetylator status significantly affects drug concentrations
• Highlighted the potential benefits of therapeutic drug monitoring in tuberculosis treatments