What question did this study set out to answer?

To explore the relationship between poststroke epilepsy and vascular cognitive disorder in young stroke patients.

March 16, 2026Open Access

Poststroke epilepsy is associated with vascular cognitive disorder in young stroke patients: The ODYSSEY study

Puntos clave

To explore the relationship between poststroke epilepsy and vascular cognitive disorder in young stroke patients.
Analyzed associations between poststroke epilepsy and vascular cognitive disorder
Evaluated cognitive impairment in attention and working memory domains
Investigated the implications of the 'second-hit hypothesis'
Identified significant associations between poststroke epilepsy and major vascular cognitive disorder
Found cognitive impairment specifically in attention and working memory areas
Supported the notion that secondary injuries worsen cognitive decline

Resumen

We found independent associations between PSE and major VCD, and between PSE and cognitive impairment in the attention and working memory domain. This could support the "second-hit hypothesis," in which epilepsy following a primary injury relates directly to increased cognitive impairment with a subcortical neuropsychological profile.

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Cite This Study

Reitsma et al. (Sat,) studied this question.

synapsesocial.com/papers/69b79e538166e15b153ab86d https://doi.org/https://doi.org/10.1002/epi.70200

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