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March 17, 2026The Brazilian Journal of Infectious DiseasesOpen Access

Pancytopenia and Hepatosplenomegaly as an Atypical Manifestation of Pyelonephritis With Multiple Abscesses

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Authors

TPT. PrataMMMariana Ramos Peixoto MeloMOMateus Roberto de Oliveira

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Overview

Atypical manifestations of pyelonephritis with abscesses cause pancytopenia in a 46-year-old woman, highlighting diagnostic challenges.

Key Points

  • To explore the atypical presentation of pancytopenia and hepatosplenomegaly due to pyelonephritis with abscesses.
  • Case report of a 46-year-old female with severe anemia and hepatosplenomegaly.
  • Abdominal CT confirmed localized renal infection and microabscesses.
  • Urine culture identified multidrug-susceptible Escherichia coli.
  • Prolonged antibiotic therapy was administered, followed by monitoring.
  • Patient presented with severe anemia (hemoglobin: 3.6 g/dL) and acute kidney injury (creatinine: 6.11 mg/dL).
  • CT revealed bilateral inflammatory renal process with multiple hypodense areas.
  • Treatment with antibiotics led to normalization of renal function and resolution of pancytopenia.

Cite This Study

Prata et al. (2026) studied this question.

synapsesocial.com/papers/69b8ef36deb47d591b8c5322https://doi.org/10.1016/j.bjid.2026.105054
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