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March 17, 2026The Brazilian Journal of Infectious Diseases0 citationsOpen Access

Intestinal Spirochetosis Caused by Syphilis Leading to Chronic Diarrhea

Intestinal Spirochetosis Due to Syphilis as a Cause of Chronic Diarrhea in an Immunocompetent Patient

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Authors

NSNazareth Fabíola Rocha SetúbalFAFernando Socorro de AlmeidaLCLuisa Campos Camargos

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Overview

Case report identifies intestinal spirochetosis causing chronic diarrhea in an immunocompetent male, suggesting critical need for accurate diagnostic strategies.

Key Points

  • To highlight a rare case of intestinal spirochetosis due to syphilis presenting as chronic diarrhea.
  • Patient evaluated for symptoms including diarrhea and abdominal cramps.
  • Serologic testing conducted for syphilis, HIV, and hepatitis.
  • Colonoscopy performed revealing mucosal abnormalities.
  • Biopsy confirmed presence of spirochetes and chronic colitis.
  • Patient treated with benzathine penicillin.
  • Chronic diarrhea persisted for five months before identification.
  • Reactive VDRL test indicated syphilis infection.
  • Colonoscopy showed suggestive signs of ulcerative colitis.
  • Treatment led to complete resolution of symptoms.

Cite This Study

Setúbal et al. (2026) studied this question.

synapsesocial.com/papers/69b8ef52deb47d591b8c560ahttps://doi.org/10.1016/j.bjid.2026.104791
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