PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 17, 2026Current Pharmaceutical Design0 citations

Jiawei Zaoqi Decoction Attenuates Polycystic Ovary Syndrome by Inhibiting AGE-RAGE-Mediated Cell Senescence of Granulosa Cells

View Full Paper
HTHong TangXOXuenong OuyangXCXuet Er Chong

Key Points

  • The research aims to evaluate the effects of Jiawei Zaoqi Decoction on polycystic ovary syndrome and its underlying mechanisms.
  • Examined the impact of JWZQD on granulosa cell senescence.
  • Analyzed active compounds quercetin and fisetin.
  • Assessed the modulation of AGE-RAGE pathway.
  • JWZQD significantly reduces granulosa cell senescence associated with PCOS.
  • Quercetin and fisetin are identified as key active compounds.
  • Inhibition of AGE-RAGE pathway is linked to the therapeutic effects.

Abstract

JWZQD mitigates PCOS by modulating AGE-RAGE-mediated granulosa-cell senescence through its active compounds quercetin and fisetin. This study supports the clinical potential of JWZQD as an alternative or complementary therapy for PCOS.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Tang et al. (2026) studied this question.

synapsesocial.com/papers/69b8f10fdeb47d591b8c5e46https://doi.org/10.2174/0113816128423816251229112509
Ask AI
Helpful
Bookmark
Share
View Full Paper