Retrospective Analysis of Incidence and Etiology of Severe Infections in Children Receiving Therapy for High‐Risk Neuroblastoma: A Large Single‐Center Experience

Key Points

• The study aims to analyze the incidence and causes of severe infections in children undergoing therapy for high-risk neuroblastoma.
• Retrospective analysis of data from children receiving therapy for high-risk neuroblastoma.
• Assessment of infection incidence and related mortality during treatment.
• Evaluation of the types of infections and their potential causes.
• Severe infections occurred frequently but had low related mortality rates.
• The incidence of invasive fungal diseases was low despite no systematic preventive measures.
• Findings provide a benchmark for understanding infection risk in the context of modern immunotherapy and CAR-T treatments.

Abstract