Visible-Light-Induced Bi 2 O 3 Catalysis toward 2-fold gem -Difluoroalkylation of Quinoxalinones

Key Points

• The goal is to achieve selective gem-difluoroalkylation of quinoxalinones using Bi2O3 as a catalyst under visible-light exposure.
• Utilized Bi2O3 as a photocatalyst under visible-light irradiation.
• Performed 2-fold gem-difluoroalkylation on quinoxalinones.
• Evaluated selectivity at C3 and C5 positions.
• Achieved high yields with exclusive selectivity at C3 and C5 positions.
• Demonstrated broad substrate generality.
• Showed potential for product diversification through scale-up.

Abstract