Development and Validation of an Automated Pediatric Cancer Staging Calculator Using the Toronto Pediatric Cancer Stage Guidelines

Key Points

• The aim is to develop and validate an automated staging calculator for pediatric cancers using Toronto guidelines.
• Developed an automated staging tool based on Toronto Pediatric Cancer Stage Guidelines.
• Validated the tool against expert human judgment for consistency and accuracy.
• Implemented a workflow that flags uncertain cases for human review.
• Achieved approximately 97% accuracy in staging pediatric cancers compared to human experts.
• Demonstrated excellent consistency across independent runs of the tool.
• Approximately 30% of cases required human adjudication due to uncertainty.

Abstract