In-situ Forming Thermally Shrinkable Electrospun Nanofiber Membranes for Wound Healing

Key Points

• To evaluate the effectiveness of a thermo-responsive electrospun dressing for wound healing.
• Developed a self-shrinking electrospun dressing.
• Applied dressing directly on skin to assess contraction and wound closure.
• Conducted experiments on mice to monitor healing outcomes over 24 hours.
• Achieved 70% active contraction upon contact with skin.
• Resulted in 60% wound closure in mice within 24 hours.
• Demonstrated nearly complete healing in the observed time frame.

Abstract